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Archive for the ‘Migraine Medication’ Category

migraine picture_111609The tough reality is that migraine has no cure.  The best one can do is to learn to prevent or manage the pain.  Here, we’ll focus on new available drug treatments for you.

Topiramate

Topiramate is a drug used for epilepsy.  Now, it’s approved in various countries for migraine prevention.  Clinical trials indicate that the drug is well received by the patients and it can lessen migraines by 50%.  A dosage of 25mg is recommended and to be increased by 25mg increments per week as required.  At the 100mg dose, side effects manifested were fatigue, nausea, upper respiratory tract infections and diarrhoea.

Zonisamide

Zonisamide is a newer drug for epilepsy treatment and is aimed at migraine prevention.  It’s reported to decrease migraine by 50% in the patients.  In others, headaches were slashed by 25%.  Typical side effects were fatigue and anxiety.  However, the drug was generally tolerated by the study participants.

Botulinum Toxin

Popularly known as “botox”, this drug is not yet approved for headache and migraine treatment.  Nevertheless, it can still be administered by a doctor. People getting the drug for cosmetic purposes noticed they had reduced headaches and migraines. Clinical studies showed that migraines had declined by one-third.

Occipital Nerve Block Injection

Anaesthetic agent lidocaine and bupivacaine are injected in the occipital nerve.  The effect was immediate and majority experienced no side effects, except for dizziness.  This is used when the migraine has already started.

Levetiracetam

This is another anti-epileptic drug proven to dodge migraines.  However, it can be efficacious for a transformed migraine.  Minimum dosage used ranges from 1500mg to 2000mg.  Manifested side effects are anxiety and discomfort.

Petasites

This is a plant extract having anti-spasmodic and analgesic properties and is believed to reduce swelling.  Though further study is needed, preliminary results show the decline in migraines by 50%.

Coenzyme Q10 (CoQ10)

CoQ10 is a naturally occurring supplement used to repair impaired oxygen metabolism for migraine treatment.  Studies show that it can cut migraine episodes by up to half.  Generally, no side effect is experience.  Right dosages are still being further investigated.

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migraine picture_110609Migraine medications work differently on migraineurs (migraine sufferers).  What may remedy some, may actually be triggers for others.  Fortunately, another ray of hope may shine anew on migraineurs who’re in continuous search for a new migraine cureLevadex, an orally inhaled drug formulated to cure migraine, is being developed by Map Pharmaceuticals (MAP) and is currently at the concluding stage.  It contains a new formulation of dihydroergotamine (DHE), an intravenously administered drug used in clinical settings to treat migraines.

How Levadex Works

The individual can dispense Levadex themselves using MAP’s Tempo inhaler.  As the drug is inhaled, it gets quickly absorbed into the lungs and bloodstream.  The medication flows to the brain and nerves to end the pain, without producing serious side effects.  Levadex offered quick and continued migraine pain relief from as fast as 10 minutes and to last up to two days after dosing. The drug puts together the multiple benefits of action that permit DHE to prevent the onset of a migraine, control the pain, reduce the swelling and crush migraine at any point of the migraine cycle.  Studies showed considerable improvement in pain relief, nausea and sensitivity to light and sound.

Side Effects

The study indicated no serious unfavourable side effects in the trial.  The most common adverse consequences of the drug use were the medication aftertaste and nausea.  On the flipside, the most infrequent side effects were chest pain or chest discomfort.  Furthermore, the lungs showed no change in activity, as gauged by the spirometry (measurement of the air entering and exiting the lungs using a spirometer).

As the product is still at the testing stage, it may take some time before it becomes available in the market.  So to the millions of migraine sufferers, just a little more wait and this promising drug may just do wonders for you.  Don’t forget to consult your physician before trying this or any other drug.

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migraine picture_103009_v1If parents can shield their children from migraine pain, they would, in a heartbeat.  It is always agonizing for parents to see their kids wrenching in pain.  But take heart, you can do something for them.  Before reading on, an important caveat, ALWAYS consult your doctor before giving your children any medication.  Below are some ideas that might help.

Sumatriptan

Sumatriptan belongs to a group of drugs called triptans.  Triptans remedy migraines and headaches by constricting the blood vessels. Imigran is the brand name of Sumatriptan and may be taken at the onset of a headache.  Sumatriptan comes in tablet form for older children and nasal spray for the younger ones.  The tablet form is not recommended for those under 18 years old, except only as prescribed by a physician.  Though the tablet is effective for adults, not much research has been done to determine its efficacy on children’s migraine.  Nasal spray is advised for children 12 and above and is likewise obtainable via prescription.  Studies show that 65% of children who took the spray experienced less pain while 40% felt completely better.  Possible side effects of the drug are dizziness, weakness, drowsiness, feeling hot and nose irritation.

Paracetamol

Paracetamol is a common painkiller and are usually in tablet form.  Parents can dissolve the tablet for easier dispensing.  Better yet, give younger children the liquid pain killer Calpol. Though the effectiveness of paracetamol in kids isn’t backed up by studies, it’s nevertheless prescribed by doctors to alleviate children’s migraine. Be wary with dispensing the right dosage for your child.  Taking too much may lead to severe liver damage or worse, cause more headaches.

Ibuprofen and other NSAIDs

Ibuprofen and non-steroidal anti-inflammatory drugs (NSAID) are also pain killers.  Calprofen is a liquid ibuprofen for kids who can’t swallow a pill. Diclofenac, an NSAID, are available over-the-counter for children over 14.  Most NSAIDs are available only with prescription.  Though NSAIDs are suitable for adults, it hasn’t been proven helpful for children. Nonetheless, it is sometimes recommended for kids.  NSAID can sometimes instigate an upset stomach in kids or worsen asthma.

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toradolSpecialists give migraine  sufferers prescribed drugs to lessen the incidence or length of their headaches, and some to prevent the pain when they believe a headache coming on.  Now and again, though, the pain is impervious and heavy-duty pain prescribed drugs are indispensable.

Non-prescription NSAIDs, non-steroidal anti-inflammatories, help a lot of people reduce their migraine pain, but when they are not adequate in amount, professionals may suggest a prescription version.  Toradol (ketorolac) is a prescription-strength NSAID experts can hand out to migraine  sufferers with moderate to severe pain that is not reacting to other pain relievers.  It is obtainable in a tablet form, but is typically dispensed in emergency rooms and injected for migraines

Toradol has several potentially injurious side effects patients should to be informed of and must be utilized  with prudence.  It can cause queasiness, tiredness, faintness, itching, diarrhea, fluid retention, and perforation or bleeding of the gastrointestinal tract.

It should not be taken by migraine  sufferers who are allergic to other NSAIDs or aspirin.  Patients with a prior incident of gastrointestinal bleeding, high blood pressure, or a history of kidney and liver conditions should stay away from ketorolac.  It should be avoided by pregnant women and the elderly as well.

Patients who have been unproductively seeking to remedy their migraine at home with over the counter NSAIDs need to let their physician or emergency room personnel know.  Ketorolac should not be doled out until other NSAIDs have cleared the body to thwart potential overdose-related obstacles.

Due to potentially dangerous drug interactions, patients need to let their physicians know about all their drugs, not just ones taken for migraines.  Toradol should not be meted out to anyone currently taking blood thinners, tranquilizers, diuretics, lithium, and identifiable types of antidepressants, methotrexate, or ACE inhibitors for blood pressure.

Toradol may supply relief when no relief from the pain can be felt, but should be taken with tremendous carefulness.

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